| Frequency-dependent
magnetic properties of iron oxide nanoparticles
for magnetic hyperthermia |
In
hyperthermia cancer treatment a tumor is selectively
exposed to high temperatures in order to kill cancer
cells. Biofunctionalized iron oxide nanoparticles
are currently under active investigation as a mechanism
for selective heating through the application of
AC magnetic fields. The REU student will work with
the Majetich group to synthesize monodisperse iron
oxide nanoparticles of different sizes and form
dispersions of various concentrations, either in
water or in agar as a tissue phantom. The UG student
will then measure the frequency-dependent hysteresis
loops and equilibrium temperatures. Finite element
modeling of the heat diffusion equation will be
used to predict size and concentration effects
on the equilibrium temperature, which will be compared
with the experimental results. |
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