2007 REU Seminar at CMU

Research Experiences for Undergraduates
Materials Research at Carnegie Mellon University

Kris Noel Dahl
Assistant Professor
Department of Biomedical Engineering
Carnegie Mellon University

“Structure, organization and mechanical properties of subcellular materials”

Wednesday, July 18, 2007
12 PM Seminar
Location: Roberts Hall Microscopy Computer Cluster
Refreshments will be served in Roberts Hall 140.

Inside of a cell there are numerous mechanically important structures such as the actin cytoskeleton, microtubule network and intermediate filament systems. We study primarily the organization of actin filaments and nuclear intermediate filament proteins known as lamins. These proteins provide structure, architecture and resistance to applied forces. Interestingly, since they are in living systems, they are constantly reorganized, their concentrations change and the molecules that they interact with changes as well. Although the structure, organization and viscoelasticity obey the same rules of material physics as artificial polymeric materials, the dynamic nature of these cellular molecules allow for the study of unique properties which combine the fields of engineering and cell biology.

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